We deliver streamlined solutions to enable patients faster access to innovative medicines
Literature Review
&
Evidence Synthesis
Our unique approach to conducting systematic literature reviews and indirect treatment comparisons helps us deliver submission-ready results in >80% less time*.
Systematic Literature Review
Evidence Synthesis
Localisation
Our team can generate robust, high quality literature reviews including:
​
​
-
Systematic literature reviews for submissions and evidence synthesis
-
Targeted literature reviews
-
Rapid literature reviews
Our team have extensive knowledge and experience with evidence synthesis methods including:​
​
-
Indirect treatment comparisons
-
Network meta-analysis
-
Matching-adjusted indirect comparisons
-
Multi-level network meta-regression
Our team have supported many countries globally with localisations and adaptations of HTA deliverables:​
​
-
Adaptation of deliverable reports to suit local requirements
-
Localisation of SLR and evidence synthesis deliverables according to local methodological guidelines
Our standardised tools* and solutions enable us to rapidly build and develop high quality and rigorous economic models for pricing, decision-making, and submission purposes.
Cost-Effectiveness Models
Health Economic Tools
Localisation
-
Early models
-
Disease agnostic models
-
Global economic models
-
Technical and strategic model QC and validation
-
Advisory & strategic support with economic modelling
-
Budget impact models
-
Cost per response models
-
Cost consequence models
-
Price-volume trade-off models
-
Bespoke models
-
Adaptation of deliverable reports to suit local requirements
-
Modification of health economic tools according to local methodological guidelines
The Evimed team has considerable knowledge and experience in developing, reviewing, and localising health economic models, and have worked across multiple therapeutic areas including oncology, immunology, neurosciences, respiratory, vaccines, and eyecare.
Health Economic Modelling
Statistical Data Analysis
With our deep technical expertise and knowledge, we can perform statistical analyses for HTA submissions, economic modelling, and publications.
Health Economics & Outcomes
Post-hoc Analysis of Clinical Trials
Our team have extensive experience in conducting statistical analyses to generate inputs for health economic assessments, outcomes research, and bespoke analyses to support reimbursement dossiers and secondary publications.​
-
Quality of life analyses
-
Health-state utility values
-
Survival analysis
-
Treatment switching
-
Adverse events
-
Cost inputs
-
Disutility
-
Post-hoc analysis of clinicals to support reimbursement dossiers in line with local guidelines
-
Analyses using tailored methodological approaches to support publications
We have extensive experience developing HTA strategies, understanding evidence requirements, and preparing for submissions in all stages of drug development.
HTA & Submission Strategy
Trial Design and Evidence Planning
Early Evaluation and Decision-Making
​
-
Advice on overall HTA & reimbursement submissions strategy
-
Expected HTA & reimbursement outcomes based on planned programme and efficacy/safety profile
-
Identification of risks and mitigation strategies
​
-
Assessment of proposed development programme against competitors & agency expectations
-
Identification of risks, mitigation strategies, and potential changes to development programme to support desired outcomes
​​
-
Assessment of reimbursement potential of early pipeline assets
-
Trade-off assessments for milestone or launch decision
-
Evaluation of business development opportunities
The Evimed team has extensive experience in HTA, collectively contributing to over 100 submissions across multiple geographies. The team has also supported the design of pivotal programs to maximize acceptability for HTA, development of HTA & submission strategies, and the early evaluation of development programs.